The state of Virginia currently has 35 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Richmond, Charlottesville, Norfolk and Fairfax.
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: UVA Health Orthopedic Center, Charlottesville, Virginia
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Carilion Roanoke Memorial Hospital, Roanoke, Virginia
Conditions: Chronic Pain
A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)
Recruiting
Evaluation of the efficacy of LX9211 compared to placebo in reducing DPNP.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Lexicon Investigational Site (130), Manassas, Virginia +1 locations
Conditions: Diabetic Peripheral Neuropathic Pain
Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with interstitial cystitis/bladder pain syndrome, compared to placebo.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: Urology of Virginia, PLLC, Virginia Beach, Virginia
Conditions: Interstitial Cystitis/Bladder Pain Syndrome
A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/30/2024
Locations: The Chronic Pelvic Pain Center, Vienna, Virginia
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)
Recruiting
The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2024
Locations: Velocity Clinical Research - Hampton, Hampton, Virginia +2 locations
Conditions: Painful Lumbosacral Radiculopathy
Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy
Recruiting
This is a two-arm randomized clinical trial in which 80 participants with Vitamin D deficiency and scheduled to begin taxane-based chemotherapy will be randomized to either: 1) prescribed vitamin D replacement or 2) standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Neuropathic Pain
Decreasing Long-term Opioid Use in Cancer Survivors
Recruiting
This is a feasibility pilot trial assessing a behavioral intervention for chronic pain among disease-free cancer survivors to decrease long-term opioid dependence.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Pain, Chronic Pain, Cancer Pain, Survivorship
Insula Neuromodulation for Chronic Neuropathic Pain
Recruiting
This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/10/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Neuropathic Pain, Chronic Pain
Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain
Recruiting
This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/10/2024
Locations: University of Virginia UVA Health, University Hospital, Charlottesville, Virginia
Conditions: Cancer of Head and Neck, Pain, Face, Pain, Neck
Trial Readiness and Endpoint Assessment in LGMD R1
Recruiting
This is a 24-month, observational study of 100 participants with Limb Girdle Muscular Dystrophy type R1, also known as CAPN3.
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
05/06/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A, Limb Girdle Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type R1, LGMD2A
Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
Recruiting
This study involves imaging the skin movements of surface tissue on the back. A clinician will perform assessment and intervention procedures manually, using manual and light movements of stretch and compression.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/26/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Tissue Pain